The most common concern I hear every day is “but is it safe?”. For most of our mothers, hormone therapy wasn’t an option, or it was taken away. My own mother was 50 when the Women’s Health Initiative (WHI) headlines hit in 2002, and like millions of other women, she was never given the chance to start hormones. That moment changed the trajectory of midlife medicine, but the story was not what it seemed.

Postpartum and overwhelmed, Emily Sadri, NP, began questioning everything she knew about blood sugar, hormones, and midlife metabolism. This piece shares the personal experience that reshaped her clinical approach—and why GLP-1 medications are about so much more than weight loss.